KI-67 Antikörper (Antigen Identified By Monoclonal Antikörper Ki-67) (AA 1250-1300)

Details for Product anti-MKI67 Antibody No. ABIN677858, Anbieter: Anmelden zum Anzeigen
Antigen
  • MKI67
  • kia
  • mki67
  • MGC132156
  • D630048A14Rik
  • Ki-67
  • Ki67
  • KIA
  • MIB-1
  • antigen identified by monoclonal antibody Ki-67
  • antigen identified by monoclonal antibody Ki 67
  • MKI67
  • mki67
  • Mki67
Epitop
AA 1250-1300
92
54
50
18
18
15
14
14
8
6
5
5
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
457
112
71
17
16
9
4
2
1
Wirt
Kaninchen
260
158
32
9
5
3
Klonalität
Polyklonal
Konjugat
Dieser KI-67 Antikörper ist unkonjugiert
17
13
11
10
10
8
7
6
5
4
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
187
184
158
120
119
105
85
73
16
12
12
11
6
3
3
3
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human Ki67
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung Ki-67 (MKI67 Antibody Abstract)
Hintergrund

Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Subcellular location: Nucleus

Synonyms: KIA, MIB-, MIB-1, PPP1R15, Antigen KI-67, MKI67

Gen-ID 4288
UniProt P46013
Pathways Glycosaminoglycan Metabolic Process
Applikationshinweise IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Formalin-fixed and paraffin-embedded human cervical carcinoma labeled with Rabbit Ant...
Immunohistochemistry (IHC) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Formalin-fixed and paraffin-embedded human oral squamous cell carcinoma labeled with ...
Immunohistochemistry (IHC) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Generously provided by Markus Linder from Medical University Vienna as part of the Bi...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Image provided by One World Lab validation program. HL60 cells were stained with bs-2...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Formalin-fixed and paraffin-embedded human oral squamous cell carcinoma labeled with ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Formalin-fixed and paraffin-embedded human cervical carcinoma labeled with Rabbit Ant...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Paraformaldehyde-fixed, paraffin embedded human stomach cancer, Antigen retrieval by ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Paraformaldehyde-fixed, paraffin embedded rat testes tissue, Antigen retrieval by boi...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1250-1300) antibody (ABIN677858) Paraformaldehyde-fixed, paraffin embedded human cervical cancer, Antigen retrieval by...
Produkt verwendet in: Thompson, Rahim, Arnold, Hielscher: "Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands." in: PLoS ONE, Vol. 12, Issue 2, pp. e0172067, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Antognelli, Gambelunghe, Muzi, Talesa et al.: "Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica ..." in: Free radical biology & medicine, Vol. 92, pp. 110-25, 2016 (PubMed). (Probematerial (Species): Human).

Li, Zhu, Qiu: "Constructing aptamer anchored nanovesicles for enhanced tumor penetration and cellular uptake of water soluble chemotherapeutics." in: Acta biomaterialia, Vol. 35, pp. 269-79, 2016 (PubMed).

Drel, Tan, Barnes, Gorin, Lee, Wagner: "Centrality of bone marrow in the severity of gadolinium-based contrast-induced systemic fibrosis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 9, pp. 3026-38, 2016 (PubMed).

Yang, Li, Zhu, Wang, Chen, Bai: "Hydroxysafflor yellow A inhibits angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-?B signaling pathway in H22 tumor-bearing mice." in: European journal of pharmacology, Vol. 754, pp. 105-14, 2015 (PubMed).

Olianas, Dedoni, Onali et al.: "Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 ..." in: Biochemical pharmacology, Vol. 95, Issue 4, pp. 311-23, 2015 (PubMed).

Zhang, Song, Pang, Zhang, Wan, Yuan, Wu, Liu: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, 2015 (PubMed).

Luo, Chen, Zhang, Chen, Li: "Pharmacokinetics and antitumor efficacy of micelles assembled from multiarmed amphiphilic copolymers with drug conjugates in comparison with drug-encapsulated micelles." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, Vol. 98, pp. 9-19, 2015 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Kim, Lim, Kim, Kim, Kim, Tian, Park, Park, Choung: "The oncoprotein, gankyrin, is up-regulated in middle ear cholesteatoma." in: Acta oto-laryngologica, Vol. 134, Issue 3, pp. 238-43, 2014 (PubMed).

Ma, Yu, He, Xu, Wu, Xia, Guo, Wang, Ye, Zhang, Tao: "Involvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibition." in: OncoTargets and therapy, Vol. 7, pp. 637-43, 2014 (PubMed).

Ye, Zheng, Fan, Qin, Li, Tang, Ai, Zhang, Bian, Dang, Huang, Zhou, Zhou, Xiong, Yan, Ma, Li: "Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice." in: PLoS ONE, Vol. 9, Issue 7, pp. e103298, 2014 (PubMed).

Li, Li, Yi, Luo, Guo, Pan, Gu: "Amphiphilic peptide dendritic copolymer-doxorubicin nanoscale conjugate self-assembled to enzyme-responsive anti-cancer agent." in: Biomaterials, Vol. 35, Issue 35, pp. 9529-45, 2014 (PubMed).

Luo, Zhang, Chen, Wei, Zhang, Li: "Antimetastasis and antitumor efficacy promoted by sequential release of vascular disrupting and chemotherapeutic agents from electrospun fibers." in: International journal of pharmaceutics, Vol. 475, Issue 1-2, pp. 438-449, 2014 (PubMed).

Pan, She, Guo, Luo, Yi, Gu: "PEGylated dendritic diaminocyclohexyl-platinum (II) conjugates as pH-responsive drug delivery vehicles with enhanced tumor accumulation and antitumor efficacy." in: Biomaterials, Vol. 35, Issue 38, pp. 10080-92, 2014 (PubMed).

Zhao, Li, Katzenellenbogen, Lau, Taylor, Bagchi, Bagchi: "Estrogen-Induced CCN1 is Critical for Establishment of Endometriosis-like Lesions in Mice." in: Molecular endocrinology (Baltimore, Md.), pp. me20141080, 2014 (PubMed).

Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, 2014 (PubMed).

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