RANKL Antikörper (AA 210-317)
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- Target Alle RANKL (TNFSF11) Antikörper anzeigen
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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Bindungsspezifität
- AA 210-317
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Reaktivität
- Human, Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RANKL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Kaninchen, Ratte
- Homologie
- Dog
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RANKL
- Isotyp
- IgG
- Top Product
- Discover our top product TNFSF11 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).
: "Atorvastatin-induced osteoclast inhibition reduces orthodontic relapse." in: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, Vol. 151, Issue 3, pp. 528-538, (2017) (PubMed).
: "Denervation effectively aggravates rat experimental periodontitis." in: Journal of periodontal research, Vol. 52, Issue 6, pp. 1011-1020, (2017) (PubMed).
: "Intermittent administration of parathyroid hormone ameliorated alveolar bone loss in experimental periodontitis in streptozotocin-induced diabetic rats." in: Archives of oral biology, Vol. 83, pp. 76-84, (2017) (PubMed).
: "Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway." in: International journal of molecular medicine, Vol. 37, Issue 2, pp. 329-38, (2016) (PubMed).
: "Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis." in: Molecular medicine reports, Vol. 14, Issue 2, pp. 1054-60, (2016) (PubMed).
: "Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway." in: Chemico-biological interactions, Vol. 256, pp. 188-97, (2016) (PubMed).
: "Bone fracture healing is delayed in splenectomic rats." in: Life sciences, Vol. 173, pp. 55-61, (2016) (PubMed).
: "Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 919-924, (2015) (PubMed).
: "Expression of colony-stimulating factor 1 is associated with occurrence of osteochondral change in pigmented villonodular synovitis." in: Tumour biology, Vol. 36, Issue 7, pp. 5361-7, (2015) (PubMed).
: "Expression of neuropeptides and bone remodeling-related factors during periodontal tissue regeneration in denervated rats." in: Journal of molecular histology, Vol. 46, Issue 2, pp. 195-203, (2015) (PubMed).
: "Oral administration of 5-hydroxytryptophan aggravated periodontitis-induced alveolar bone loss in rats." in: Archives of oral biology, Vol. 60, Issue 5, pp. 789-98, (2015) (PubMed).
: "A Crucial Role of IL-17 in Bone Resorption During Rejection of Fresh Bone Xenotransplantation in Rats." in: Cell biochemistry and biophysics, (2014) (PubMed).
: "Efficacy and safety of echinacoside in a rat osteopenia model." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 926928, (2013) (PubMed).
: "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." in: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).
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The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).
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- Target
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
- Andere Bezeichnung
- RANKL (TNFSF11 Produkte)
- Synonyme
- CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, TNFSF11 antikoerper, Ly109l antikoerper, OPG antikoerper, Trance antikoerper, cd254 antikoerper, odf antikoerper, opgl antikoerper, optb2 antikoerper, rankl antikoerper, sodf antikoerper, tnfsf11 antikoerper, trance antikoerper, TNF superfamily member 11 antikoerper, tumor necrosis factor (ligand) superfamily, member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, TNF superfamily member 11 L homeolog antikoerper, TNFSF11 antikoerper, Tnfsf11 antikoerper, TNFRSF11B antikoerper, tnfsf11.L antikoerper
- Hintergrund
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Synonyms: ODF, OPGL, sOdf, CD254, OPTB2, RANKL, TRANCE, hRANKL2, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11
Background: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
- Gen-ID
- 8600
- UniProt
- O14788
- Pathways
- NF-kappaB Signalweg
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