CD130/gp130 Antikörper (pTyr905)

Produktnummer ABIN650804

Der Kaninchen Polyklonal anti-CD130/gp130 Antikörper wird verwendet zum Nachweis von CD130/gp130 in Proben von Human. Er wurde validiert für DB.

Kurzübersicht für CD130/gp130 Antikörper (pTyr905) (ABIN650804)

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD130/gp130 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB21495

Produktdetails anti-CD130/gp130 Antikörper

Bindungsspezifität: pTyr905

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL6ST Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y905 of human IL6ST.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CD130/gp130

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Andere Bezeichnung: IL6ST

Hintergrund: IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein.

Molekulargewicht: 103537

Gen-ID: 3572

NCBI Accession: NP_001177910, NP_002175, NP_786943

UniProt: P40189

Pathways: JAK-STAT Signalweg, Cellular Glucan Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Cancer Immune Checkpoints