CYP1A2 Antikörper (Middle Region)

Produktnummer ABIN951775

Produktdetails anti-CYP1A2 Antikörper

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Bindungsspezifität: AA 262-290, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse CYP1A2 (Center). Other species not tested.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of Human CYP1A2. Genename: CYP1A2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Andere Bezeichnung: CYP1A2 (CYP1A2 Produkte)

Synonyme: CP12 antikoerper, P3-450 antikoerper, P450(PA) antikoerper, CYP1A2 antikoerper, CYPIA2 antikoerper, P450-PM4 antikoerper, Cyp1a1 antikoerper, P450-3 antikoerper, CYPD45 antikoerper, P-450d antikoerper, RATCYPD45 antikoerper, CYP1A5 antikoerper, CP450 antikoerper, CYP-IA2 antikoerper, cytochrome P450 family 1 subfamily A member 2 antikoerper, cytochrome P450 1A2 antikoerper, cytochrome P450 LM4 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 2 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 2 antikoerper, cytochrome P450 1A2-like antikoerper, CYP1A2 antikoerper, LOC100328937 antikoerper, Cyp1a2 antikoerper, VDBG_06455 antikoerper, LOC101825565 antikoerper, LOC102130662 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.Synonyms: CYPIA2, Cytochrome P(3)450, Cytochrome P450 1A2, Cytochrome P450 4, Cytochrome P450-P3

Molekulargewicht: 58294 Da

Gen-ID: 1544

NCBI Accession: NP_000752