GGA3 Antikörper (AA 400-415)
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- Target Alle GGA3 Antikörper anzeigen
- GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
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Bindungsspezifität
- AA 400-415
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Reaktivität
- Human, Orang-Utan, Makake, Schimpanse
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GGA3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody is directed against GGA3 protein.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Chimpanzee, Macaque, Orangutan.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography
- Immunogen
- Synthetic peptide corresponding to amino acids 400-415 of Human GGA3
- Isotyp
- IgG
- Top Product
- Discover our top product GGA3 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000 - 1/50000. Western Blot: 1/500 - 1/3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.62 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
- Andere Bezeichnung
- GGA3 (GGA3 Produkte)
- Synonyme
- C230037M19Rik antikoerper, mKIAA0154 antikoerper, golgi associated, gamma adaptin ear containing, ARF binding protein 3 antikoerper, Gga3 antikoerper, GGA3 antikoerper
- Hintergrund
- GGA3 (also known as ADPribosylation factor binding protein GGA3, Golgilocalized, gamma ear-containing, ARF-binding protein 3, Gamma-adaptin related protein 3) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. This protein mediates the ARFdependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. GGA1 is a monomeric protein that interacts with SORT1, SORL1, LRP3, GGA binding partner (GGABP) and P200, GGA1 and GGA2 as well as RABEP1, RABGEF1 and type-I membrane proteins M6PR/CD-MPR, IGF2R/CIMPR and BACE1. GGA3 is a ubiquitously expressed membrane-associated protein that is localized to TGN and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ADP-ribosylation factor-binding protein GGA3, Golgi-localized gamma ear-containing ARF-binding protein 3, KIAA0154
- Gen-ID
- 23163
- NCBI Accession
- NP_001166174
- UniProt
- Q9NZ52
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