GGA3 Antikörper (AA 400-425)
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- Target Alle GGA3 Antikörper anzeigen
- GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
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Bindungsspezifität
- AA 400-425
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Reaktivität
- Human, Schimpanse
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GGA3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Hersteller Produkt- Nr.
- 600-401-893
- Hersteller
- Rockland
- Verwendungszweck
- GGA3 Antibody
- Kreuzreaktivität (Details)
- This affinity purified antibody is directed against human GGA3 protein.
- Produktmerkmale
- Synonyms: rabbit anti-GGA3 antibody, GGA-3, GGA 3, ADP-ribosylation factor-binding protein GGA3, Golgi-localized gamma ear-containing ARF-binding protein 3
- Aufreinigung
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
- Sterilität
- Sterile filtered
- Immunogen
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Immunogen: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 400-425 of Human GGA3.
Immunogen Type: Conjugated Peptide
- Isotyp
- IgG
- Top Product
- Discover our top product GGA3 Primärantikörper
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- Applikationshinweise
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect bands at 78 kDa in size corresponding to GGA3 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:3,000
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.48 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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- Target
- GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
- Andere Bezeichnung
- GGA3 (GGA3 Produkte)
- Hintergrund
- Background: GGA3 (also known as ADP-ribosylation factor binding protein GGA3, Golgi-localized, gamma ear-containing, ARF-binding protein 3, Gamma-adaptin related protein 3) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. This protein mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. GGA1 is a monomeric protein that interacts with SORT1, SORL1, LRP3, GGA binding partner (GGABP) and P200, GGA1 and GGA2 as well as RABEP1, RABGEF1 and type-I membrane proteins M6PR/CD-MPR, IGF2R/CI-MPR and BACE1. GGA3 is a ubiquitously expressed membrane-associated protein that is localized to TGN and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gen-ID
- 23163, 20336267
- UniProt
- Q9NZ52
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