CACNB2 Antikörper (Middle Region)

Produktnummer ABIN501437

Produktdetails anti-CACNB2 Antikörper

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HLADYLEAYW KATHPPSSSL PNPLLSRTLA TSSLPLSPTL ASNSQGSQGD

Homologie: Cow: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 605 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Andere Bezeichnung: CACNB2 (CACNB2 Produkte)

Synonyme: CACNLB2 antikoerper, CAVB2 antikoerper, MYSB antikoerper, AW060387 antikoerper, CAB2 antikoerper, Cavbeta2 antikoerper, Cchb2 antikoerper, Cacnlb2 antikoerper, Cacnb2 antikoerper, CACNB2 antikoerper, CACNB2.2 antikoerper, cacnb2a antikoerper, im:7141271 antikoerper, si:dkey-32m20.2 antikoerper, calcium voltage-gated channel auxiliary subunit beta 2 antikoerper, calcium channel, voltage-dependent, beta 2 subunit antikoerper, calcium channel, voltage-dependent, beta 2b antikoerper, CACNB2 antikoerper, Cacnb2 antikoerper, cacnb2b antikoerper

Hintergrund: CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Alias Symbols: CACNLB2, FLJ23743, MYSB, CAVB2
Protein Interaction Partner: REM1, PRKACA,
Protein Size: 605

Molekulargewicht: 68 kDa

Gen-ID: 783

NCBI Accession: NM_201590, NP_963884

UniProt: Q08289

Pathways: Skeletal Muscle Fiber Development