BAFF Antikörper (C-Term)

Produktnummer ABIN499401

Produktdetails anti-BAFF Antikörper

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: Recognizes BAFF

Aufreinigung: Ion Exchange Chromatography

Immunogen: A peptide corresponding to amino acids near the carboxy terminus of Human BAFF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: BAFF antibody can be used for detection of BAFF at 0.25 to 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: CD257 / BAFF (TNFSF13B Produkte)

Synonyme: BAFF antikoerper, BLYS antikoerper, CD257 antikoerper, DTL antikoerper, TALL-1 antikoerper, TALL1 antikoerper, THANK antikoerper, TNFSF20 antikoerper, ZTNF4 antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, TNFSF13B antikoerper, RGD1561519 antikoerper, RGD1560810 antikoerper, BLyS antikoerper, D8Ertd387e antikoerper, zTNF4 antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, zgc:172115 antikoerper, TNF superfamily member 13b antikoerper, TNF receptor superfamily member 13C antikoerper, tumor necrosis factor (ligand) superfamily, member 13b antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, tumor necrosis factor superfamily member 13b antikoerper, TNFSF13B antikoerper, TNFRSF13C antikoerper, Tnfsf13b antikoerper, Tnfrsf13c antikoerper, tnfsf13b antikoerper

Hintergrund: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kappaB and c-jun N-terminal Kinase) (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R (5,6). BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis (5).Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4

Gen-ID: 10673

NCBI Accession: NP_006564

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response