COL1A1 Antikörper (C-Term)
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- Target Alle COL1A1 Antikörper anzeigen
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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Bindungsspezifität
- AA 1185-1207, C-Term
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COL1A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Collagen alpha-1(I) chain(COL1A1) detection. Tested with WB, IHC-P in Mouse,Rat.
- Sequenz
- YDFSFLPQPP QEKSQDGGRY YRA
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Collagen alpha-1(I) chain(COL1A1) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: collagen, type I, alpha 1
Protein Name: Collagen alpha-1(I) chain - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Collagen I (1185-1207aa YDFSFLPQPPQEKSQDGGRYYRA), different from the related human sequence by three amino acids, and identical to the related rat sequence.
- Isotyp
- IgG
- Top Product
- Discover our top product COL1A1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Dimethyl α-ketoglutarate reduces CCl4-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells." in: Biochemical and biophysical research communications, Vol. 481, Issue 1-2, pp. 90-96, (2017) (PubMed).
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: "Continuing treatment with Salvia miltiorrhiza injection attenuates myocardial fibrosis in chronic iron-overloaded mice." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124061, (2016) (PubMed).
: "Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6407-15, (2016) (PubMed).
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The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).
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- Target
- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
- Andere Bezeichnung
- COL1A1 (COL1A1 Produkte)
- Synonyme
- OI4 antikoerper, Col1a-1 antikoerper, Cola-1 antikoerper, Cola1 antikoerper, Mov-13 antikoerper, Mov13 antikoerper, COLIA1 antikoerper, col1a1 antikoerper, MGC52532 antikoerper, COL1A1 antikoerper, COL1A2 antikoerper, alpha1(I) antikoerper, cb21 antikoerper, sb:cb21 antikoerper, sb:cb384 antikoerper, wu:fa99c12 antikoerper, wu:fb02c06 antikoerper, alpha3(I) antikoerper, col1a3 antikoerper, hm:zeh0348 antikoerper, wu:fa95h05 antikoerper, wu:fd02a10 antikoerper, wu:fj59a10 antikoerper, collagen type I alpha 1 chain antikoerper, collagen, type I, alpha 1 antikoerper, collagen, type I, alpha 1 S homeolog antikoerper, collagen alpha-1(I) chain antikoerper, collagen type I alpha 2 chain antikoerper, collagen, type I, alpha 1a antikoerper, collagen 1a1 antikoerper, collagen, type I, alpha 1b antikoerper, COL1A1 antikoerper, Col1a1 antikoerper, col1a1.S antikoerper, LOC397571 antikoerper, COL1A2 antikoerper, col1a1a antikoerper, col1a1 antikoerper, col1a1b antikoerper
- Hintergrund
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Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. And this gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.
Synonyms: Alpha 1 type I collagen | Alpha 2 type I collagen | Alpha-1 type I collagen | CO1A1 | COL1A1 | Collagen alpha-1 chain | Collagen alpha1(I) chain | Collagen alpha-1(I) chain | Collagen I | Collagen Type 1 | Collagen type I alpha 1 | Collagen type I alpha 2 | collagen, type I, alpha 1 | OI4 | Pro alpha 1(I) collagen | Type I procollagen | P11087 - Gen-ID
- 12842
- UniProt
- P11087
- Pathways
- Sensory Perception of Sound, Autophagie, Growth Factor Binding
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