WNT6 Antikörper (Middle Region)
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- Target Alle WNT6 Antikörper anzeigen
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WNT6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human WNT6
- Top Product
- Discover our top product WNT6 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 365 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
- Andere Bezeichnung
- WNT6 (WNT6 Produkte)
- Synonyme
- WNT6 antikoerper, si:dkey-31m21.2 antikoerper, Wnt6 antikoerper, AA409270 antikoerper, Wnt-6 antikoerper, Xwnt-6 antikoerper, wnt-6 antikoerper, wnt6-A antikoerper, xWnt6 antikoerper, Wnt family member 6 antikoerper, wingless-type MMTV integration site family, member 6b antikoerper, wingless-type MMTV integration site family, member 6 antikoerper, Wnt family member 6 S homeolog antikoerper, WNT6 antikoerper, Wnt6 antikoerper, wnt6b antikoerper, wnt6.S antikoerper
- Hintergrund
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The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365 - Molekulargewicht
- 37 kDa
- Gen-ID
- 7475
- NCBI Accession
- NM_006522, NP_006513
- UniProt
- Q9Y6F9
- Pathways
- WNT Signalweg, Tube Formation
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