Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PIP5K1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PIP5K1B.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Qin, Li, Pan, Wu: "Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22544-8, (2009) (PubMed).
Bolomini-Vittori, Montresor, Giagulli, Staunton, Rossi, Martinello, Constantin, Laudanna: "Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module." in: Nature immunology, Vol. 10, Issue 2, pp. 185-94, (2009) (PubMed).
Target
PIP5K1B
(Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))
MSS4 antikoerper, STM7 antikoerper, AI844522 antikoerper, Pip5k1a antikoerper, Pipk5a antikoerper, Pipk5b antikoerper, MGC80809 antikoerper, pip5k1b antikoerper, zgc:101046 antikoerper, wu:fj29b05 antikoerper, wu:fj93b05 antikoerper, zgc:92316 antikoerper, phosphatidylinositol-4-phosphate 5-kinase type 1 beta antikoerper, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta antikoerper, phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog antikoerper, phosphatidylinositol-4-phosphate 5-kinase, type I, beta a antikoerper, phosphatidylinositol-4-phosphate 5-kinase, type I, beta antikoerper, phosphatidylinositol 4-phosphate 5-kinase type-1 beta antikoerper, phosphatidylinositol-4-phosphate 5-kinase, type I, beta b antikoerper, PIP5K1B antikoerper, Pip5k1b antikoerper, pip5k1b.L antikoerper, pip5k1ba antikoerper, pip5k1b antikoerper, LOC100472550 antikoerper, pip5k1bb antikoerper
Hintergrund
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.