PAK6 Antikörper (AA 116-146)

Produktnummer ABIN392439

Produktdetails anti-PAK6 Antikörper

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Bindungsspezifität: AA 116-146

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PAK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-146 amino acids from human PAK6.

Klon: RB1237

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6 (PAK6 Produkte)

Synonyme: PAK5 antikoerper, 4732456M09 antikoerper, pak6 antikoerper, si:ch211-158b22.3 antikoerper, p21 (RAC1) activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6b antikoerper, PAK6 antikoerper, Pak6 antikoerper, pak6b antikoerper

Hintergrund: The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

Molekulargewicht: 74869

Gen-ID: 56924

NCBI Accession: NP_001122100, NP_001122101, NP_001263646, NP_001263647, NP_064553

UniProt: Q9NQU5