MAP2K5 Antikörper (Mitogen-Activated Protein Kinase Kinase 5) (AA 127-156)

Details for Product anti-MAP2K5 Antibody No. ABIN392401, Anbieter: Anmelden zum Anzeigen
Antigen
  • Mek5
  • HsT17454
  • MAPKK5
  • MEK5
  • PRKMK5
  • AI324775
  • AI428457
  • Mapkk5
  • Prkmk5
  • fb73f02
  • wu:fb73f02
  • zgc:172137
  • ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5
  • ATMAP2K_ALPHA
  • ATMEK5
  • ATMKK5
  • MAP KINASE KINASE 5
  • MAP kinase kinase 5
  • MAP2K_A
  • mitogen activated protein kinase kinase 5
  • mitogen-activated protein kinase kinase 5
  • Map2k5
  • MAP2K5
  • map2k5
  • MKK5
Alternativen
anti-Human MAP2K5 Antikörper für ELISA
Epitop
AA 127-156, Ser149
33
30
15
15
15
15
14
11
10
8
6
6
6
5
4
4
3
2
2
2
2
1
1
1
1
1
Reaktivität
Human
168
89
82
11
7
7
6
4
3
3
3
3
2
2
2
2
1
1
Wirt
Kaninchen
162
16
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser MAP2K5 Antikörper ist unkonjugiert
9
9
9
5
5
5
5
5
5
5
5
5
5
4
4
4
4
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
110
64
47
28
24
22
4
3
2
1
1
1
Optionen
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Immunogen This MAP2K5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 AA from human MAP2K5.
Klon RB12745
Isotyp Ig
Spezifität This MAP2K5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S149 of human MAP2K5.
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung MAP2K5 (MAP2K5 Antibody Abstract)
Hintergrund MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.
Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MAP2K5
Molekulargewicht 48837 DA
Gen-ID 5607
UniProt Q13163
Forschungsgebiet Protein Modifications, Cell Cycle, Cell Structure
Pathways MAPK Signalweg, Neurotrophin Signalübertragung
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-MAP2K5 Antikörper (Mitogen-Activated Protein Kinase Kinase 5) (AA 127-156) (ABIN392401) Western blot analysis of MAP2K5 (arrow) using rabbit polyclonal MAP2K5 Antibody (S149...
Immunohistochemistry (IHC) image for anti-MAP2K5 Antikörper (Mitogen-Activated Protein Kinase Kinase 5) (AA 127-156) (ABIN392401) Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with MAP2K5...
Allgemeine Veröffentlichungen English, Pearson, Hockenberry, Shivakumar, White, Cobb: "Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31588-92, 1999 (PubMed).