Lumican (LUM) (AA 64-91), (N-Term) Antikörper

Details zu Produkt Nr. ABIN391881, Anbieter: Anmelden zum Anzeigen
Antigen
  • MGC64527
  • zgc:86661
  • ldc
  • slrr2d
  • DKFZp468L1116
  • LDC
  • SLRR2D
  • Ldc
  • lumican
  • lumican L homeolog
  • LUM
  • lum.L
  • lum
  • CpipJ_CPIJ010209
  • Lum
Epitop
AA 64-91, N-Term
21
11
6
5
4
3
2
2
2
1
1
1
1
Reaktivität
Human, Maus
73
40
27
4
4
4
3
3
2
1
1
Wirt
Kaninchen
75
7
Klonalität (Klon)
Polyklonal ()
Konjugat
Unkonjugiert
6
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
25
20
14
13
13
6
5
4
2
2
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 AA from the N-terminal region of human LUM.
Klon RB18422
Isotyp Ig
Spezifität This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70~100 amino acids from the N-terminal region of human LUM.
Homologie Rat (Rattus)
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Andere Bezeichnung LUM (LUM Antibody Abstract)
Hintergrund LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Synonyms: Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, SLRR2D, LDC, LUM
Molekulargewicht 38429 DA
Gen-ID 4060
UniProt P51884
Forschungsgebiet Cell Signaling, Cancer, Cell Structure
Pathways Glycosaminoglycan Metabolic Process
Applikationshinweise WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Lumican (LUM) (AA 64-91), (N-Term) antibody (ABIN391881) Western blot analysis of LUM Antibody (N-term) (ABIN391881) in mouse bladder tissue l...
Immunohistochemistry (IHC) image for anti-Lumican (LUM) (AA 64-91), (N-Term) antibody (ABIN391881) Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with LUM Antibo...
Flow Cytometry (FACS) image for anti-Lumican (LUM) (AA 64-91), (N-Term) antibody (ABIN391881) LUM Antibody (N-term) (ABIN391881) flow cytometric analysis of Hela cells (right hist...
Allgemeine Veröffentlichungen Wang, Li, Xiao, Jia, Jiao, Guo, Zhang: "High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes." in: Investigative ophthalmology & visual science, Vol. 50, Issue 4, pp. 1546-51, 2009 (PubMed).

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