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CDKL5 Antikörper (C-Term)

CDKL5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3556 unconjugated
Produktnummer ABIN391362
  • Target Alle CDKL5 Antikörper anzeigen
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    Bindungsspezifität
    • 15
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 982-1012, C-Term
    Reaktivität
    • 49
    • 32
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 60
    • 1
    Kaninchen
    Klonalität
    • 60
    • 1
    Polyklonal
    Konjugat
    • 17
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDKL5 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 32
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CDKL5 (STK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 982-1012 amino acids from the C-terminal region of human CDKL5 (STK9).
    Klon
    RB3556
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CDKL5 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    Andere Bezeichnung
    CDKL5 (STK9) (CDKL5 Produkte)
    Synonyme
    issx antikoerper, stk9 antikoerper, EIEE2 antikoerper, ISSX antikoerper, STK9 antikoerper, BC038161 antikoerper, Stk9 antikoerper, cyclin dependent kinase like 5 antikoerper, cyclin-dependent kinase-like 5 antikoerper, CDKL5 antikoerper, cdkl5 antikoerper, Cdkl5 antikoerper
    Hintergrund
    Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.
    Molekulargewicht
    107519
    Gen-ID
    6792
    NCBI Accession
    NP_001032420, NP_003150
    UniProt
    O76039
    Pathways
    Regulation of Cell Size
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