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Nanog Antikörper (pSer71)

NANOG Reaktivität: Human IF, DB Wirt: Kaninchen Polyclonal RB18920 unconjugated
Produktnummer ABIN390032
  • Target Alle Nanog (NANOG) Antikörper anzeigen
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Bindungsspezifität
    • 16
    • 16
    • 12
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer71
    Reaktivität
    • 134
    • 60
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 122
    • 18
    • 3
    • 1
    Kaninchen
    Klonalität
    • 117
    • 27
    Polyklonal
    Konjugat
    • 79
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nanog Antikörper ist unkonjugiert
    Applikation
    • 113
    • 60
    • 44
    • 42
    • 26
    • 26
    • 19
    • 18
    • 17
    • 17
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Dot Blot (DB)
    Homologie
    Pr
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S71 of human Nanog.
    Klon
    RB18920
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NANOG Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Andere Bezeichnung
    Nanog (NANOG Produkte)
    Synonyme
    2410002E02Rik antikoerper, ENK antikoerper, ecat4 antikoerper, NANOG antikoerper, hacp antikoerper, wu:fd19e04 antikoerper, wu:fd20a07 antikoerper, zgc:193933 antikoerper, Nanog homeobox antikoerper, nanog homeobox antikoerper, Nanog antikoerper, NANOG antikoerper, nanog antikoerper
    Hintergrund
    NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
    Molekulargewicht
    34620
    Gen-ID
    79923
    NCBI Accession
    NP_079141
    UniProt
    Q9H9S0
    Pathways
    Stem Cell Maintenance
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