Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180]. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
CMT2L antikoerper, DHMN2 antikoerper, E2IG1 antikoerper, H11 antikoerper, HMN2 antikoerper, HMN2A antikoerper, HSP22 antikoerper, MGC64408 antikoerper, hsc70 antikoerper, wu:fb01g06 antikoerper, wu:fi48b06 antikoerper, fc09c11 antikoerper, wu:fc04b04 antikoerper, wu:fc09c11 antikoerper, zgc:64202 antikoerper, AU018630 antikoerper, AW413033 antikoerper, Cryac antikoerper, D5Ucla4 antikoerper, H11K antikoerper, HSP20-like antikoerper, Hsp22 antikoerper, heat shock protein family B (small) member 8 antikoerper, heat shock protein family B (small) member 8 L homeolog antikoerper, heat shock protein 8 antikoerper, heat shock protein b8 antikoerper, HSPB8 antikoerper, hspb8.L antikoerper, hspa8 antikoerper, hspb8 antikoerper, Hspb8 antikoerper
Hintergrund
Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22