HSPB8 Antikörper (AA 1-196)

Produktnummer ABIN3016167

Produktdetails anti-HSPB8 Antikörper

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Bindungsspezifität: AA 1-196

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8/HSP22 (NP_055180.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: HSPB8 (HSPB8 Produkte)

Synonyme: CMT2L antikoerper, DHMN2 antikoerper, E2IG1 antikoerper, H11 antikoerper, HMN2 antikoerper, HMN2A antikoerper, HSP22 antikoerper, MGC64408 antikoerper, hsc70 antikoerper, wu:fb01g06 antikoerper, wu:fi48b06 antikoerper, fc09c11 antikoerper, wu:fc04b04 antikoerper, wu:fc09c11 antikoerper, zgc:64202 antikoerper, AU018630 antikoerper, AW413033 antikoerper, Cryac antikoerper, D5Ucla4 antikoerper, H11K antikoerper, HSP20-like antikoerper, Hsp22 antikoerper, heat shock protein family B (small) member 8 antikoerper, heat shock protein family B (small) member 8 L homeolog antikoerper, heat shock protein 8 antikoerper, heat shock protein b8 antikoerper, HSPB8 antikoerper, hspb8.L antikoerper, hspa8 antikoerper, hspb8 antikoerper, Hspb8 antikoerper

Hintergrund: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.,HSPB8,CMT2L,DHMN2,E2IG1,H11,HMN2,HMN2A,HSP22,Signal Transduction,Neuroscience,Neurodegenerative Diseases,HSPB8

Molekulargewicht: 21 kDa

Gen-ID: 26353

UniProt: Q9UJY1