PPP2R5E Antikörper (C-Term)

Produktnummer ABIN374131

Produktdetails anti-PPP2R5E Antikörper

Target: PPP2R5E (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-LKRGLRRDGI IPT

Spezifität: This antibody detects PPP2R5E at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Rat, Dog and Cow.
Species reactivity (tested):Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_006237.1 Genename: PPP2R5E

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 55 kDa and 45 kDa bands seen in mouse brain extracts. Please note that the two bands may correspond to two different isoforms. Two isoforms ofthe epsilon mRNA have been detected in Northern blots (J Biol Chem 1996 Sep6,271(36): 22081-9).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu PPP2R5E

Target: PPP2R5E (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E))

Andere Bezeichnung: PPP2R5E (PPP2R5E Produkte)

Synonyme: 4633401M22Rik antikoerper, AI449017 antikoerper, B56beta antikoerper, wdb2 antikoerper, ppp2r5e antikoerper, ppp2r5e1 antikoerper, PPP2R5E antikoerper, ppp2r5e2 antikoerper, wdb1 antikoerper, zgc:85613 antikoerper, protein phosphatase 2 regulatory subunit B'epsilon antikoerper, protein phosphatase 2, regulatory subunit B', epsilon antikoerper, protein phosphatase 2 regulatory subunit B', epsilon antikoerper, protein phosphatase 2, regulatory subunit B', epsilon isoform b antikoerper, protein phosphatase 2 regulatory subunit B', beta antikoerper, protein phosphatase 2, regulatory subunit B', epsilon isoform a antikoerper, PPP2R5E antikoerper, Ppp2r5e antikoerper, ppp2r5eb antikoerper, ppp2r5e antikoerper, ppp2r5b.L antikoerper, ppp2r5e.S antikoerper, ppp2r5ea antikoerper

Hintergrund: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.Synonyms: PP2A B subunit B'epsilon isoform, PP2A B subunit B56 epsilon isoform, PP2A B subunit PR61 epsilon isoform, PP2A B subunit R5 epsilon isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

Gen-ID: 5529

NCBI Accession: NP_006237

UniProt: Q16537

Pathways: PI3K-Akt Signalweg