Phospholipase C gamma 2 Antikörper (AA 1215-1219)
Kurzübersicht für Phospholipase C gamma 2 Antikörper (AA 1215-1219) (ABIN363097)
Target
Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1215-1219
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Spezifität
- The antibody detects endogenous level of total PLC-g2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 1215-1219 (F-L-Y-D-T) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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Applikationshinweise
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Phospholipase C gamma 2 (PLCG2)
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Andere Bezeichnung
- PLC-gamma2
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Hintergrund
- The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
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Molekulargewicht
- 150 kDa
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NCBI Accession
- NP_002652
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UniProt
- P16885
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Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Target
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