The antibody detects endogenous level of total CaMKII protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogen
Peptide sequence around AA 284-288 (Q-E-T-V-D) derived from Human CaMKII. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
CAMK antikoerper, CAMK-II antikoerper, CAMKG antikoerper, 5930429P18Rik antikoerper, Camkg antikoerper, calcium/calmodulin dependent protein kinase II gamma antikoerper, calcium/calmodulin-dependent protein kinase II gamma antikoerper, CAMK2G antikoerper, Camk2g antikoerper
Hintergrund
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity J Bossuyt, K Helmstadter, X Wu, et al. (2008) Ca2+/Calmodulin-Dependent Protein Kinase II {delta} and Protein Kinase D Overexpression Reinforce - Circulation Research, 102(6):695-702.