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NFKB2 Antikörper (AA 864-868)

NFKB2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362509
  • Target Alle NFKB2 Antikörper anzeigen
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    Bindungsspezifität
    • 16
    • 14
    • 13
    • 13
    • 11
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 864-868
    Reaktivität
    • 136
    • 96
    • 60
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 135
    • 7
    Kaninchen
    Klonalität
    • 124
    • 17
    • 1
    Polyklonal
    Konjugat
    • 80
    • 12
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NFKB2 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 48
    • 41
    • 28
    • 22
    • 17
    • 16
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of total NFkB-p100/p52 protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 864-868 (E-D-S-A-Y) derived from Human NFkB-p100, p52. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product NFKB2 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    Andere Bezeichnung
    NFkappaB-p100/p52 (NFKB2 Produkte)
    Synonyme
    NF-kappaB2 antikoerper, lyt antikoerper, p49 antikoerper, p49/p100 antikoerper, p50B antikoerper, p52 antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antikoerper, Nfkb2 antikoerper
    Hintergrund
    NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
    Molekulargewicht
    120 kDa
    NCBI Accession
    NP_001070
    UniProt
    Q00653
    Pathways
    Toll-Like Receptors Cascades
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