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ALOX5AP Antikörper (AA 94-124)

ALOX5AP Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN360268
  • Target Alle ALOX5AP Antikörper anzeigen
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    AA 94-124
    Reaktivität
    • 14
    • 2
    • 1
    Human
    Wirt
    • 12
    • 3
    Kaninchen
    Klonalität
    • 14
    • 1
    Polyklonal
    Konjugat
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALOX5AP Antikörper ist unkonjugiert
    Applikation
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes ALOX5AP.
    Cellular Localization: Nucleus membrane. Endoplasmic reticulum membrane.
    Aufreinigung
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94~124 amino acids selected from the Center region of Human ALOX5AP. Genename: ALOX5AP
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ALOX5AP Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Andere Bezeichnung
    ALOX5AP / FLAP (ALOX5AP Produkte)
    Synonyme
    fj65d02 antikoerper, zgc:63982 antikoerper, wu:fj65d02 antikoerper, flap antikoerper, al5ap antikoerper, Alox5ap antikoerper, ALOX5AP antikoerper, Flap antikoerper, FLAP antikoerper, arachidonate 5-lipoxygenase-activating protein antikoerper, arachidonate 5-lipoxygenase activating protein antikoerper, alox5ap antikoerper, ALOX5AP antikoerper, Alox5ap antikoerper
    Hintergrund
    Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Synonyms: Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein
    Gen-ID
    241, 9606
    UniProt
    P20292
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