MST1R Antikörper (C-Term, N-Term)

Produktnummer ABIN359935

Produktdetails anti-MST1R Antikörper

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Bindungsspezifität: AA 22-51, C-Term, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MST1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes CD136/RON.

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with two KLH conjugated synthetic peptides between 22~51 amino acids from the N-terminal and C-terminal regions of Human RON. Genename: MST1R

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MST1R

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Andere Bezeichnung: CD136 / MST1R (MST1R Produkte)

Synonyme: CD136 antikoerper, CDw136 antikoerper, PTK8 antikoerper, RON antikoerper, Fv-2 antikoerper, Fv2 antikoerper, Ron antikoerper, STK antikoerper, Cdw136 antikoerper, Ptk8 antikoerper, Stk antikoerper, macrophage stimulating 1 receptor antikoerper, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antikoerper, MST1R antikoerper, Mst1r antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: MSP receptor, Macrophage-Stimulating 1 Receptor, Macrophage-stimulating protein receptor, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain, PTK8, RON, p185-Ron

Gen-ID: 4486, 9606

UniProt: Q04912

Pathways: RTK Signalweg