MLLT1
Reaktivität: Human
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
MLLT1
(MLLT1, super elongation complex subunit (MLLT1))
MGC84026 antikoerper, MLLT1 antikoerper, ENL antikoerper, LTG19 antikoerper, YEATS1 antikoerper, AA407901 antikoerper, BAM11 antikoerper, MLLT1, super elongation complex subunit antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antikoerper, Mllt1 antikoerper, MLLT1 antikoerper, mllt1.L antikoerper, mllt1 antikoerper
Hintergrund
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.Synonyms: LTG19, YEATS domain-containing protein 1, YEATS1, mixed-lineage leukemia translocated to 1