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TNK2 Antikörper (pTyr518)
TNK2
Reaktivität: Human
EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TNK2 Antikörper
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Target
Alle TNK2 Antikörper anzeigen
TNK2
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Bindungsspezifität
Alle Epitope für TNK2 Antikörper
pTyr518
Reaktivität
Alle Reaktivitäten für TNK2 Antikörper
Human
Wirt
Alle Wirte für TNK2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNK2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNK2 Antikörper
Dieser TNK2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNK2 Antikörper
Enzyme Immunoassay (EIA)
Spezifität
This antibody detects TNK2 / ACK1 pTyr518.
Aufreinigung
Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.
Isotyp
Ig Fraction
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Details zu TNK2
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Target
TNK2
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Andere Bezeichnung
TNK2 / ACK1 (TNK2 Produkte )
Synonyme
ACK antikoerper, ACK-1 antikoerper, ACK1 antikoerper, p21cdc42Hs antikoerper, AW552477 antikoerper, Ack antikoerper, Cdgip antikoerper, Pyk1 antikoerper, ack1 antikoerper, ackb antikoerper, tnk2 antikoerper, tnk2b antikoerper, wu:fj16g04 antikoerper, zgc:154019 antikoerper, tyrosine kinase non receptor 2 antikoerper, tyrosine kinase, non-receptor, 2 antikoerper, tyrosine kinase, non-receptor, 1 antikoerper, TNK2 antikoerper, Tnk2 antikoerper, tnk1 antikoerper
Hintergrund
ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
Molekulargewicht
114327 Da
Gen-ID
10188, 9606
UniProt
Q07912
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