RFC2 Antikörper (N-Term)

Produktnummer ABIN357963

Produktdetails anti-RFC2 Antikörper

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects RFC2 (N-term).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RFC2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RFC2

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Andere Bezeichnung: RFC2 / RFC40 (RFC2 Produkte)

Synonyme: 2610008M13Rik antikoerper, 40kDa antikoerper, AI326953 antikoerper, Recc2 antikoerper, RFC40 antikoerper, replication factor C subunit 2 antikoerper, replication factor C (activator 1) 2 antikoerper, LOC100231971 antikoerper, RFC2 antikoerper, Rfc2 antikoerper

Hintergrund: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. RFC2 is the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of RFC2 gene has been associated with Williams syndrome.Synonyms: Activator 1 40 kDa subunit, Activator 1 subunit 2, RF-C 40 kDa subunit, Replication factor C 40 kDa subunit, Replication factor C subunit 2

Molekulargewicht: 39157 Da

Gen-ID: 5982, 9606

UniProt: P35250

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA