SLC16A1 Antikörper (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1)) (AA 207-236)

Details for Product anti-SLC16A1 Antibody No. ABIN357906, Anbieter: Anmelden zum Anzeigen
Antigen
  • MCT1a
  • cb517
  • zgc:55682
  • slc16a1
  • MGC52993
  • SLC16A1
  • DKFZp469B1212
  • HHF7
  • MCT
  • MCT1
  • RATMCT1
  • RNMCT1
  • AL022710
  • Mct1
  • solute carrier family 16 (monocarboxylic acid transporters), member 1
  • solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
  • solute carrier family 16 (monocarboxylate transporter), member 1
  • slc16a1
  • SLC16A1
  • Slc16a1
Epitop
AA 207-236, Middle Region
17
17
17
9
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Human
82
20
4
Wirt
Kaninchen
62
24
Klonalität
Polyklonal
Konjugat
Dieser SLC16A1 Antikörper ist unkonjugiert
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
63
32
27
22
21
20
12
4
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207~236 amino acids from the Center region of Human SLC16A1. Genename: SLC16A1
Isotyp Ig
Spezifität This antibody detects SLC16A1 (Center).
Reinigung Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Andere Bezeichnung SLC16A1 (SLC16A1 Antibody Abstract)
Hintergrund SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT (Garcia et al., 1994 [PubMed 8124722]).Synonyms: MCT 1, MCT1, Monocarboxylate transporter 1, Solute carrier family 16 member 1
Molekulargewicht 53958 Da predicted from amino acid sequence. Theoretical pI: 8.91 Da
Gen-ID 6566, 9606
UniProt P53985
Forschungsgebiet Transporters
Applikationshinweise ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Bilder des Herstellers
 image for anti-Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) (AA 207-236), (Middle Region) antibody (ABIN357906) anti-Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) (AA 207-236), (Middle Region) antibody
Allgemeine Veröffentlichungen Pinheiro, Longatto-Filho, Scapulatempo, Ferreira, Martins, Pellerin, Rodrigues, Alves, Schmitt, Baltazar: "Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 452, Issue 2, pp. 139-46, 2008 (PubMed).

Otonkoski, Jiao, Kaminen-Ahola, Tapia-Paez, Ullah, Parton, Schuit, Quintens, Sipilä, Mayatepek, Meissner, Halestrap, Rutter, Kere: "Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells." in: American journal of human genetics, Vol. 81, Issue 3, pp. 467-74, 2007 (PubMed).

Martín-Venegas, Rodríguez-Lagunas, Geraert, Ferrer: "Monocarboxylate transporter 1 mediates DL-2-Hydroxy-(4-methylthio)butanoic acid transport across the apical membrane of Caco-2 cell monolayers." in: The Journal of nutrition, Vol. 137, Issue 1, pp. 49-54, 2006 (PubMed).

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