Stim2 Antikörper (Middle Region)

Produktnummer ABIN318882

Produktdetails anti-Stim2 Antikörper

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stim2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognises an internal region of stromal interaction molecule-2 (STIM2), a ubiquitously expressed type I membrane protein, of which at least three isoforms have been identified.

Aufreinigung: Purified

Immunogen: A 17 amino acid peptide located near the centre of human STIM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5 - 1.0 μg/mL, detects a band of approximately 105 kDa in A20 cell lysates
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Stim2

Target: Stim2 (Stromal Interaction Molecule 2 (Stim2))

Andere Bezeichnung: STIM2 (Stim2 Produkte)

Synonyme: STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper

Hintergrund: In T-lymphocytes and other haematopoietic cells, the mechanism for increasing intracellular Ca2+, following antigen mediated T-cell activation, is through the store-operated Ca2+ release-activated Ca2+ (CRAC) channels. STIM1 is reported to activate CRAC channels upon Ca2+ depletion. Whereas, STIM2 acts to inhibit the STIM1-mediated store-operated Ca2+ entry, and forms complexes with STIM1, suggesting that these molecules may play a co-ordinated role in controlling Ca2+ entry.Synonyms: KIAA1482, Stromal interaction molecule 2

Gen-ID: 57620

NCBI Accession: NP_065911

UniProt: Q9P246

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling