L-Selectin Antikörper (AA 39-372)

Produktnummer ABIN3043326

Produktdetails anti-L-Selectin Antikörper

Target: L-Selectin (SELL) (Selectin L (SELL))

Bindungsspezifität: AA 39-372

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
Gene Name: selectin L
Protein Name: L-selectin

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for L-selectin is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: SELL (SELL Produkte)

Synonyme: CD62L antikoerper, LAM1 antikoerper, LECAM1 antikoerper, LEU8 antikoerper, LNHR antikoerper, LSEL antikoerper, LYAM1 antikoerper, PLNHR antikoerper, TQ1 antikoerper, A.11 antikoerper, L-selectin antikoerper, LECAM-1 antikoerper, SELE antikoerper, AI528707 antikoerper, Lnhr antikoerper, Ly-22 antikoerper, Ly-m22 antikoerper, Lyam-1 antikoerper, Lyam1 antikoerper, selectin L antikoerper, selectin, lymphocyte antikoerper, SELL antikoerper, Sell antikoerper

Substanzklasse: Chemical

Hintergrund: CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Synonyms: A.11 antibody|AI528707 antibody|CD62 antigen ligand antibody|CD62 antigen-like family member L antibody|CD62L antibody|gp90 MEL antibody|gp90-MEL antibody|hLHRc antibody|IgA nephropathy, susceptibility to, included antibody|L Selectin antibody|L-selectin antibody|LAM-1 antibody|LAM1 antibody|LECAM1 antibody|LEU8 antibody|Leukocyte adhesion molecule 1 antibody|Leukocyte surface antigen Leu-8 antibody|Leukocyte surface antigen Leu8 antibody|Leukocyte-endothelial cell adhesion molecule 1 antibody|LNHR antibody|LSEL antibody|Ly-22 antibody|Ly-m22 antibody|Lyam-1 antibody|LYAM1 antibody|LYAM1_HUMAN antibody|Lymph node homing receptor antibody|Lymphocyte adhesion molecule 1 antibody|Lymphocyte antigen 22 antibody|Lymphocyte surface MEL-14 antigen antibody|MEL-14 antibody|Pln homing receptor antibody|PLNHR antibody|Selectin L antibody|Selectin, lymphocyte antibody|SELL antibody|TQ1 antibody

Gen-ID: 6402

UniProt: P14151