EPH Receptor B3 Antikörper (C-Term)

Produktnummer ABIN3042663

Produktdetails anti-EPH Receptor B3 Antikörper

Target: EPH Receptor B3 (EPHB3)

Bindungsspezifität: AA 982-998, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Ephrin type-B receptor 3(EPHB3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: SIQDMRLQMN QTLPVQV

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ephrin type-B receptor 3(EPHB3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: EPH receptor B3
Protein Name: Ephrin type-B receptor 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor B3(982-998aa SIQDMRLQMNQTLPVQV), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Andere Bezeichnung: EPHB3 (EPHB3 Produkte)

Synonyme: tck antikoerper, MGC83457 antikoerper, EPHB3 antikoerper, ETK2 antikoerper, HEK2 antikoerper, TYRO6 antikoerper, AW456895 antikoerper, Cek10 antikoerper, Etk2 antikoerper, MDK5 antikoerper, Sek4 antikoerper, Tyro6 antikoerper, CEK10 antikoerper, EK10 antikoerper, ek3 antikoerper, ephb3 antikoerper, fc62d03 antikoerper, rtk3 antikoerper, wu:fc62d03 antikoerper, zek3 antikoerper, EPH receptor B3 antikoerper, EPH receptor B3 L homeolog antikoerper, Eph receptor B3 antikoerper, eph receptor B3a antikoerper, Eph receptor tyrosine kinase antikoerper, EPHB3 antikoerper, ephb3.L antikoerper, ephb3 antikoerper, Ephb3 antikoerper, ephb3a antikoerper

Hintergrund: Ephrin Receptor EphB3, is also known as human embryo kinase2(HEK2) or Eph-like tyrosine kinase2(ETK2). HEK2, which is a member of the EPH/ELK family of tyrosine kinases, encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and 2 fibronectin repeats. The EPHB3 gene is mapped to human chromosome 3q21-qter. HEK2 interacts with 2 ligands of EPH-related kinases(LERKs), namely, LERK2(EFNB1) and LERK5(EFNB2). Coincubation of HEK2- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of HEK2 and LERK2 results in reduced kinase activity of HEK2.

Synonyms: Cek10 antibody|EK2 antibody|Embryonic kinase 2 antibody|EPH Like Tyrosine Kinase 2 antibody|EPH-like kinase 2 antibody|EphB3 antibody|EPHB3_HUMAN antibody|Ephrin receptor EphB3 antibody|Ephrin type B receptor 3 antibody|Ephrin type-B receptor 3 antibody|ETK2 antibody|HEK2 antibody|Human Embryo Kinase 2 antibody|Mdk5 antibody|Sek4 antibody|TYRO6 antibody|Tyrosine protein kinase receptor HEK2 antibody|Tyrosine protein kinase TYRO6 antibody|Tyrosine-protein kinase TYRO6 antibody

UniProt: P54753

Pathways: RTK Signalweg