SCN5A Antikörper (Internal Region)

Produktnummer ABIN303416

Produktdetails anti-SCN5A Antikörper

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SCN5A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognises SCN5A.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Amino Acids (C)ETDDQSPEKIN from an internal region of human SCN5A.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (5-10 μg/mL). ELISA (1/32000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris buffered saline containing 0.5 % BSA and 0.02 % sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid cycles of freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.

Details zu SCN5A

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Andere Bezeichnung: SCN5A (SCN5A Produkte)

Synonyme: Nav1.5 antikoerper, Nav1.5c antikoerper, SkM1 antikoerper, SkM2 antikoerper, mH1 antikoerper, CDCD2 antikoerper, CMD1E antikoerper, CMPD2 antikoerper, HB1 antikoerper, HB2 antikoerper, HBBD antikoerper, HH1 antikoerper, ICCD antikoerper, IVF antikoerper, LQT3 antikoerper, PFHB1 antikoerper, SSS1 antikoerper, VF1 antikoerper, SCAL antikoerper, sodium voltage-gated channel alpha subunit 5 antikoerper, sodium channel, voltage-gated, type V, alpha antikoerper, SCN5A antikoerper, Scn5a antikoerper

Hintergrund: Scn5a encodes the alpha subunit of the type V voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone has been shown to generate a functional channel in vitro, but it's kinetic properties are modulated by beta subunits. The type V channel has been shown to be tetrodotoxin-resistant. Scn5a null mice experience intrauterine lethality. Mutations in the SCN5A gene are responsible for several heart conditions, including the chromosome 3-linked form of long LQT and Brugada syndrome.Synonyms: CDCD2, HB1, HB2, HBBD, HH1, LQT3, Nav1.5, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5

Gen-ID: 6331

NCBI Accession: NP_000326

UniProt: Q14524