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PD-L1 Antikörper (Biotin)

PD-L1 Reaktivität: Human FACS Wirt: Maus Monoclonal MIH3 Biotin
Produktnummer ABIN2853592
  • Target Alle PD-L1 Antikörper anzeigen
    PD-L1 (CD274 (PD-L1))
    Reaktivität
    • 171
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Human
    Wirt
    • 127
    • 62
    • 17
    • 4
    • 4
    • 1
    Maus
    Klonalität
    • 108
    • 105
    • 2
    Monoklonal
    Konjugat
    • 99
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser PD-L1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 139
    • 104
    • 60
    • 40
    • 38
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody reacts with human CD274.
    Aufreinigung
    Protein A agarose
    Immunogen
    Full-length human PD-L1 transfected L cells
    Klon
    MIH3
    Isotyp
    IgG1
    Top Product
    Discover our top product PD-L1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.02 mg/mL
    Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 2 - 8 °C.
  • Target
    PD-L1 (CD274 (PD-L1))
    Andere Bezeichnung
    CD274 / PDL1 (PD-L1 Produkte)
    Synonyme
    B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper
    Hintergrund
    Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    Gen-ID
    29126
    NCBI Accession
    NP_054862
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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