FOXO4 Antikörper (Middle Region)
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- Target Alle FOXO4 Antikörper anzeigen
- FOXO4 (Forkhead Box O4 (FOXO4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Schwein, Pferd, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOXO4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- YLYQILQGIV FCHSRRVLHR DLKPQNLLID DKGTIKLADF GLARAFGIPI
- Homologie
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
- Top Product
- Discover our top product FOXO4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 505 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FOXO4 (Forkhead Box O4 (FOXO4))
- Andere Bezeichnung
- FOXO4 (FOXO4 Produkte)
- Synonyme
- FOXO4 antikoerper, foxo4 antikoerper, AFX antikoerper, AFX1 antikoerper, MLLT7 antikoerper, Afxh antikoerper, Mllt7 antikoerper, afx antikoerper, RGD1561201 antikoerper, forkhead box O4 antikoerper, forkhead box O4 L homeolog antikoerper, FOXO4 antikoerper, foxo4.L antikoerper, Foxo4 antikoerper
- Hintergrund
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FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Alias Symbols: AFX, AFX1, MGC120490, MLLT7
Protein Interaction Partner: REL, SFN, AKT1, OGT, UBC, ATXN3, MDM2, NLK, USP7, CTNNB1, CREBBP, VDR, SIRT1, SMAD3, XPO1, YWHAZ, SMAD4, FOXG1, AKT2, ESR1, PIN1, CCND1, CDKN1A,
Protein Size: 505 - Molekulargewicht
- 54 kDa
- Gen-ID
- 4303
- NCBI Accession
- NM_005938, NP_005929
- UniProt
- P98177
- Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
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