FCGR3A Antikörper (Middle Region)
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- Target Alle FCGR3A Antikörper anzeigen
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FCGR3A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DPIHLRCHSW KNTALHKVTY LQNGKGRKYF HHNSDFYIPK ATLKDSGSYF
- Homologie
- Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FCGR3A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product FCGR3A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 253 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- Andere Bezeichnung
- FCGR3A (FCGR3A Produkte)
- Synonyme
- CD16 antikoerper, CD16A antikoerper, FCG3 antikoerper, FCGR3 antikoerper, FCGRIII antikoerper, FCR-10 antikoerper, FCRIII antikoerper, FCRIIIA antikoerper, IGFR3 antikoerper, Fcgr4 antikoerper, Fc fragment of IgG receptor IIIa antikoerper, FCGR3A antikoerper, Fcgr3a antikoerper
- Hintergrund
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This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Protein Interaction Partner: SYK, ZBTB25, APP, IGHG1, GP6, SHC1, CD4, CD247, ZAP70, LCK, PTPRC, FCER1G, FCGR1A, CD38, APCS,
Protein Size: 253 - Molekulargewicht
- 27 kDa
- Gen-ID
- 2214
- NCBI Accession
- NM_001127596, NP_001121068
- UniProt
- P08637
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