PFKM Antikörper (C-Term)
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- Target Alle PFKM Antikörper anzeigen
- PFKM (phosphofructokinase, Muscle (PFKM))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PFKM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RALVFQPVAE LKDQTDFEHR IPKEQWWLKL RPILKILAKY EIDLDTSDHA
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PFKM. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PFKM
- Top Product
- Discover our top product PFKM Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 780 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PFKM (phosphofructokinase, Muscle (PFKM))
- Andere Bezeichnung
- PFKM (PFKM Produkte)
- Synonyme
- GSD7 antikoerper, PFK-1 antikoerper, PFK1 antikoerper, PFKA antikoerper, PFKX antikoerper, AI131669 antikoerper, PFK-A antikoerper, PFK-M antikoerper, Pfk-4 antikoerper, Pfk4 antikoerper, Pfka antikoerper, Pfkx antikoerper, Pfk-M antikoerper, M-PFK antikoerper, PFKM antikoerper, pfkm antikoerper, zgc:92344 antikoerper, pfk antikoerper, im:7137110 antikoerper, wu:fc58g11 antikoerper, phosphofructokinase, muscle antikoerper, phosphofructokinase, platelet antikoerper, phosphofructokinase, muscle a antikoerper, phosphofructokinase, muscle S homeolog antikoerper, phosphofructokinase, muscle b antikoerper, PFKM antikoerper, Pfkm antikoerper, PFKP antikoerper, pfkma antikoerper, pfkm.S antikoerper, pfkmb antikoerper
- Hintergrund
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Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Alias Symbols: GSD7, MGC8699, PFK-1, PFK1, PFKA, PFKX
Protein Interaction Partner: UBC, SIAH1, PFKM, SUMO2, EGFR, DCP2, DCP1A, TUBB2A, PFKP, PCBP1, UBTD1, FBXO6, LSM7, PFKL, NDUFB2, Hoxa1, CUL3, MAPK3, PCNA, SUMO1, ATP6V0A4, FHL2, DYNLL1, CAV3, NOS1, HGS,
Protein Size: 780 - Molekulargewicht
- 85 kDa
- Gen-ID
- 5213
- NCBI Accession
- NM_000289, NP_000280
- UniProt
- P08237
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt
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