CYP11A1 Antikörper (Middle Region)

Produktnummer ABIN2784683

Produktdetails anti-CYP11A1 Antikörper

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LRQKGSVHHD YRGILYRLLG DSKMSFEDIK ANVTEMLAGG VDTTSMTLQW

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP11A1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP11A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 521 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP11A1

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Andere Bezeichnung: CYP11A1 (CYP11A1 Produkte)

Synonyme: CYP11A antikoerper, CYP11A1 antikoerper, CYPXIA1 antikoerper, P450SCC antikoerper, Cyp11a antikoerper, Cypxia1 antikoerper, D9Ertd411e antikoerper, P450scc antikoerper, Scc antikoerper, cscc antikoerper, P450(scc) antikoerper, SSC antikoerper, cytochrome P450 family 11 subfamily A member 1 antikoerper, cholesterol side-chain cleavage enzyme, mitochondrial-like antikoerper, cytochrome P450 cholesterol side-chain cleavage antikoerper, cytochrome P450, family 11, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 11, subfamily A, polypeptide 1 antikoerper, CYP11A1 antikoerper, LOC101827747 antikoerper, Cyp11a1 antikoerper

Hintergrund: CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Alias Symbols: CYP11A, P450SCC, CYPXIA1
Protein Interaction Partner: SMAD9, SMAD3, SMAD2, CYP11B2, FDX1,
Protein Size: 521

Molekulargewicht: 57 kDa

Gen-ID: 1583

NCBI Accession: NM_000781, NP_000772

UniProt: P05108

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin