NTRK3 Antikörper (C-Term)
-
- Target Alle NTRK3 Antikörper anzeigen
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NTRK3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK ATPIYLDILG
- Homologie
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NTRK3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK3
- Top Product
- Discover our top product NTRK3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 825 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Andere Bezeichnung
- NTRK3 (NTRK3 Produkte)
- Synonyme
- TRKC antikoerper, gp145(trkC) antikoerper, trkC antikoerper, AW125844 antikoerper, Ntrk3_tv3 antikoerper, TrkC antikoerper, neurotrophic receptor tyrosine kinase 3 antikoerper, neurotrophic tyrosine kinase, receptor, type 3 antikoerper, NTRK3 antikoerper, Ntrk3 antikoerper
- Hintergrund
-
NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: TNK2, IRAK3, HSP90AA1, APP, SHC2, KIDINS220, DOK5, RASGRF1, MAPK3, DYNLL1, SQSTM1, SHC1, NGFRAP1, IRAK1, HTR2A, MAPK1, PTPN1, PLCG1, JUN, NTF3, NGFR, FRS2,
Protein Size: 825 - Molekulargewicht
- 89 kDa
- Gen-ID
- 4916
- NCBI Accession
- NM_002530, NP_002521
- Pathways
- RTK Signalweg, Neurotrophin Signalübertragung, Regulation of Cell Size
-