SRD5A2 Antikörper (N-Term)
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- Target Alle SRD5A2 Antikörper anzeigen
- SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SRD5A2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KHTESLKPAA TRLPARAAWF LQELPSFAVP AGILARQPLS LFGPPGTVLL
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 93%, Rabbit: 86%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SRD5A2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SRD5A2
- Top Product
- Discover our top product SRD5A2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 254 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
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Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
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- Target
- SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
- Andere Bezeichnung
- SRD5A2 (SRD5A2 Produkte)
- Synonyme
- S5AR 2 antikoerper, 5ART2 antikoerper, SRD5alpha2 antikoerper, SRD5A2 antikoerper, Srd5a2 antikoerper, CH73-233A22.6 antikoerper, wu:fk70d02 antikoerper, zgc:109942 antikoerper, zgc:112208 antikoerper, zgc:112455 antikoerper, steroid 5 alpha-reductase 2 antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) antikoerper, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2a antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2b antikoerper, SRD5A2 antikoerper, Srd5a2 antikoerper, srd5a2 antikoerper, LOC100125532 antikoerper, srd5a2a antikoerper, srd5a2b antikoerper
- Hintergrund
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This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
Alias Symbols: MGC138457
Protein Size: 254 - Molekulargewicht
- 28 kDa
- Gen-ID
- 6716
- NCBI Accession
- NM_000348, NP_000339
- UniProt
- P31213
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
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