SLC11A1 Antikörper (C-Term)

Produktnummer ABIN2781545

Produktdetails anti-SLC11A1 Antikörper

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Ziege, Pferd, Schaf, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC11A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VLLTRSCAIL PTVLVAVFRD LRDLSGLNDL LNVLQSLLLP FAVLPILTFT

Homologie: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC11A1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC11A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 550 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC11A1 Antikörper (ABIN2781545)

Usuda, Kono, Hayashi, Kawasaki, Mitsui, Shibutani, Dote, Adachi, Fujihara, Shimbo, Sun, Lu, Nakasuji: "Determination of reference concentrations of strontium in urine by inductively coupled plasma atomic emission spectrometry." in: Environmental health and preventive medicine, Vol. 11, Issue 1, pp. 11-6, (2011) (PubMed).

Details zu SLC11A1

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Andere Bezeichnung: SLC11A1 (SLC11A1 Produkte)

Synonyme: SLC11A1 antikoerper, NRAMP1 antikoerper, LSH antikoerper, NRAMP antikoerper, Bcg antikoerper, Itg antikoerper, Lsh antikoerper, Nramp1 antikoerper, Ity antikoerper, Nramp antikoerper, ity antikoerper, BCG antikoerper, solute carrier family 11 member 1 L homeolog antikoerper, solute carrier family 11 member 1 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 antikoerper, slc11a1.L antikoerper, SLC11A1 antikoerper, Slc11a1 antikoerper

Hintergrund: SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.
Alias Symbols: LSH, NRAMP, NRAMP1
Protein Size: 550

Molekulargewicht: 61 kDa

Gen-ID: 6556

NCBI Accession: NM_000578, NP_000569

UniProt: P49279

Pathways: Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus