MYCN Antikörper (Mycn) (C-Term)

Details for Product anti-MYCN Antibody No. ABIN2779428, Anbieter: Anmelden zum Anzeigen
Antigen
  • MODED
  • MYCNOT
  • N-myc
  • NMYC
  • ODED
  • bHLHe37
  • Nmuc1
  • Nmyc
  • Nmyc-1
  • Nmyc1
  • c-nmyc
  • olfactory receptor, family 8, subfamily S, member 1-like
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
  • LOC515887
  • MYCN
  • Mycn
Epitop
C-Term
15
8
4
4
4
3
3
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
93
55
30
2
2
1
1
1
1
1
Wirt
Kaninchen
59
36
Klonalität
Polyklonal
Konjugat
Dieser MYCN Antikörper ist unkonjugiert
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
71
21
18
17
16
13
5
4
3
3
3
3
2
2
1
1
Optionen
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN
Sequenz EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER
Homologie Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%
Produktmerkmale This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Andere Bezeichnung MYCN (MYCN Antibody Abstract)
Hintergrund MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
Protein Interaction Partner: TRIM32, UBC, HDAC5, NMI, MAX, CDKN2A, GRK5, ZBTB17, SIRT1, YEATS4, CSNK1E, FBXW7, PIAS2, AURKA, SP1, NTRK1, NGFR, HDAC2, CSNK2A1, YAF2, MXD1, CSNK2A2, SLC1A2,
Protein Size: 464
Molekulargewicht 50 kDa
Gen-ID 4613
NCBI Accession NM_005378, NP_005369
UniProt P04198
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 464 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-MYCN Antikörper (Mycn) (C-Term) (ABIN2779428) anti-Mycn (MYCN) (C-Term) antibody
Allgemeine Veröffentlichungen Hansford, Thomas, Keating, Burkhart, Peaston, Norris, Haber, Armati, Weiss, Marshall: "Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 34, pp. 12664-9, 2004 (PubMed).