MYCN Antikörper (AA 168-267)
Kurzübersicht für MYCN Antikörper (AA 168-267) (ABIN1680957)
Target
Alle MYCN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 168-267
-
Sequenz
- AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
-
-
- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
-
Andere Bezeichnung
- MYCN
-
Hintergrund
- This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,MYCN
-
Molekulargewicht
- 49 kDa
-
Gen-ID
- 4613
-
UniProt
- P04198
Target
-