TYK2 Antikörper (C-Term)
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- Target Alle TYK2 Antikörper anzeigen
- TYK2 (Tyrosine Kinase 2 (TYK2))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TYK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HRDLAARNVL LDNDRLVKIG DFGLAKAVPE GHEYYRVRED GDSPVFWYAP
- Homologie
- Cow: 91%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TYK2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TYK2
- Top Product
- Discover our top product TYK2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1187 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TYK2 (Tyrosine Kinase 2 (TYK2))
- Andere Bezeichnung
- TYK2 (TYK2 Produkte)
- Synonyme
- JTK1 antikoerper, tyrosine kinase 2 antikoerper, TYK2 antikoerper, Tyk2 antikoerper
- Hintergrund
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Alias Symbols: JTK1
Protein Interaction Partner: KHDRBS2, KRT40, TRAF4, HNRNPK, FHL3, COPS5, JAK3, UBC, HSP90AA1, TYK2, PTAFR, EIF2AK2, LNX1, KLF10, SOCS1, TK1, DNM2, IFNAR1, JAKMIP1, XRCC5, STAM2, PRMT5, IFNAR2, CRKL, GHR, IRS2, IL6ST, STAT2, STAT1, IL13RA1, GNB2L1, PTPN1, PTPN6, PDGFRB, PLAUR, PIK3R1,
Protein Size: 1187 - Molekulargewicht
- 134 kDa
- Gen-ID
- 7297
- NCBI Accession
- NM_003331, NP_003322
- UniProt
- P29597
- Pathways
- JAK-STAT Signalweg, Hepatitis C
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