SMARCA5 Antikörper (N-Term)

Produktnummer ABIN2779246

Produktdetails anti-SMARCA5 Antikörper

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMARCA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequenz: AGPADAEMEE IFDDASPGKQ KEIQEPDPTY EEKMQTDRAN RFEYLLKQTE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SMARCA5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1052 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMARCA5

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Andere Bezeichnung: SMARCA5 (SMARCA5 Produkte)

Synonyme: fb26d12 antikoerper, fb49g04 antikoerper, chunp6878 antikoerper, im:7146484 antikoerper, wu:fb26d12 antikoerper, wu:fb49g04 antikoerper, zgc:158434 antikoerper, smarca5 antikoerper, iswi antikoerper, SMARCA5 antikoerper, hiswi antikoerper, snf2h antikoerper, hsnf2h antikoerper, wcrf135 antikoerper, MGC79455 antikoerper, ISWI antikoerper, SNF2H antikoerper, WCRF135 antikoerper, hISWI antikoerper, hSNF2H antikoerper, 4933427E24Rik antikoerper, D030040M08Rik antikoerper, D330027N15Rik antikoerper, MommeD4 antikoerper, Snf2h antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 S homeolog antikoerper, smarca5 antikoerper, smarca5.S antikoerper, SMARCA5 antikoerper, Smarca5 antikoerper

Hintergrund: SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ISWI, SNF2H, WCRF135, hISWI, hSNF2H
Protein Interaction Partner: SUMO2, SUMO3, HIST1H3A, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, HB-1, AT5G35210, LMNA, RSF1, BAZ1A, SMARCA5, WHSC1, SS18, SSX2, UL29, RNF168, VCP, NOTCH1, IK, HDAC2, HDAC1, CHRAC1, MBD3, PHGDH, NCSTN, POLR3A, RUVBL2, RBM14, SAP18, HNRNPR, EIF4A3, B
Protein Size: 1052

Molekulargewicht: 122 kDa

Gen-ID: 8467

NCBI Accession: NM_003601, NP_003592

UniProt: O60264

Pathways: Chromatin Binding