YARS Antikörper (N-Term)

Produktnummer ABIN2778856

Produktdetails anti-YARS Antikörper

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MGDAPSPEEK LHLITRNLQE VLGEEKLKEI LKERELKIYW GTATTGKPHV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against YARS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 528 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Andere Bezeichnung: YARS (Yars Produkte)

Synonyme: CMTDIC antikoerper, TYRRS antikoerper, YRS antikoerper, YTS antikoerper, AL024047 antikoerper, AU018965 antikoerper, cb204 antikoerper, wu:fk52b08 antikoerper, YARS antikoerper, cmtdic antikoerper, tyrrs antikoerper, yrs antikoerper, yts antikoerper, CG4561 antikoerper, Dmel\\CG4561 antikoerper, TyrRS antikoerper, anon-EST:Posey261 antikoerper, dYARS antikoerper, GB10789 antikoerper, tyrosyl-tRNA synthetase antikoerper, tyrosyl-tRNA synthetase L homeolog antikoerper, tyrosyl-tRNA synthetase, putative antikoerper, tyrosine--tRNA ligase antikoerper, Tyrosyl-tRNA synthetase antikoerper, tyrosine--tRNA ligase, cytoplasmic antikoerper, YARS antikoerper, Yars antikoerper, yars antikoerper, yars.L antikoerper, MAL8P1.125 antikoerper, MEFER_RS04475 antikoerper, TyrRS antikoerper, LOC413909 antikoerper, LOC100163888 antikoerper, LOC100282315 antikoerper

Hintergrund: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. Sequence Note: The RefSeq transhttp://www.ncbi.nlm.nih.gov/projects/locusXref/oho.cgi?server= REFTRACK&frm=0x66adf650&appid=0&evId=1&evIntpar=8565&evStrpar=&frmA n=EditApp LocusXref: edit YARS(8565)cript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMTDIC, TYRRS, YRS, YTS
Protein Interaction Partner: UBC, SARNP, NRD1, HSPA8, VCAM1, ITGA4, FN1, METTL16, XRCC5, DYNC1H1, CDK2, ELANE, EIF1B, SAP18, EIF6, ARF6,
Protein Size: 528

Molekulargewicht: 59 kDa

Gen-ID: 8565

NCBI Accession: NM_003680, NP_003671

UniProt: P54577