RAE1 Antikörper (C-Term)

Produktnummer ABIN2778734

Produktdetails anti-RAE1 Antikörper

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SACCFNHNGN IFAYASSYDW SKGHEFYNPQ KKNYIFLRNA AEELKPRNKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RAE1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RAE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 368 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAE1

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Andere Bezeichnung: RAE1 (RAE1 Produkte)

Synonyme: gle2 antikoerper, mig14 antikoerper, mnrp41 antikoerper, mrnp41 antikoerper, MRNP41 antikoerper, zgc:56449 antikoerper, zgc:77723 antikoerper, 3230401I12Rik antikoerper, 41 antikoerper, D2Ertd342e antikoerper, MNRP antikoerper, MNRP41 antikoerper, MIG14 antikoerper, Mnrp41 antikoerper, dJ481F12.3 antikoerper, dJ800J21.1 antikoerper, ribonucleic acid export 1 antikoerper, RAE1 RNA export 1 homolog antikoerper, ribonucleic acid export 1 L homeolog antikoerper, rae1 antikoerper, LOC664096 antikoerper, RAE1 antikoerper, rae1.L antikoerper, Rae1 antikoerper

Hintergrund: RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: TP53, CDC37, DGCR8, YAP1, STK3, EEF2K, SOX2, HNRNPUL1, YWHAQ, UBC, FN1, ZC3HAV1, UBD, DDX39B, NUP98, MAP2, NUMA1, RNA28S5, RNA18S5, LSM14A, IGF2BP3, NXF1, TACC3, DYNLL1, KHSRP, KPNB1, ILF3, COPS6, CUL1, CUL3, Nup214, Nup188, KAT2A, PTTG1, POLR3H, FAM122B,
Protein Size: 368

Molekulargewicht: 40 kDa

Gen-ID: 8480

NCBI Accession: NM_001015885, NP_001015885

UniProt: P78406

Pathways: SARS-CoV-2 Protein Interaktom