TFAP2C Antikörper (N-Term)

Produktnummer ABIN2778628

Produktdetails anti-TFAP2C Antikörper

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Bindungsspezifität: N-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAP2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SASLIPHISG LEGGSVSARR EVYRRSDLLL PHAHALEAGL AENLGLHEMA

Homologie: Mouse: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TCFAP2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse TCFAP2C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Antigen size: 449 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TFAP2C Antikörper (ABIN2778628)

Shim, Cho, Seo, Kim, Ryu, Yoo, Yang, Kim, Bahk, Park: "Proteomic analysis of time-dependent difference of protein expression profile changes during neuronal differentiation of mouse embryonic stem cells." in: Molecules and cells, Vol. 29, Issue 3, pp. 239-44, (2010) (PubMed).

Al-Batran, Rafiyan, Atmaca, Neumann, Karbach, Bender, Weidmann, Altmannsberger, Knuth, Jäger: "Intratumoral T-cell infiltrates and MHC class I expression in patients with stage IV melanoma." in: Cancer research, Vol. 65, Issue 9, pp. 3937-41, (2005) (PubMed).

Details zu TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Andere Bezeichnung: TCFAP2C (TFAP2C Produkte)

Synonyme: erf1 antikoerper, hap-2g antikoerper, tfa2pc antikoerper, tfap2g antikoerper, ap2-gamma antikoerper, TFAP2C antikoerper, AP2-gamma antikoerper, Tcfap2c antikoerper, AP2-GAMMA antikoerper, ERF1 antikoerper, TFAP2G antikoerper, hAP-2g antikoerper, wu:fb48g05 antikoerper, wu:fb49c04 antikoerper, zgc:92088 antikoerper, ap-2g antikoerper, tfap2gamma antikoerper, AA409384 antikoerper, AP2gamma antikoerper, Ap-2.2 antikoerper, Stra2 antikoerper, transcription factor AP-2 gamma antikoerper, putative transcription factor ap-2 gamma antikoerper, transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) antikoerper, transcription factor AP-2 gamma S homeolog antikoerper, transcription factor AP-2, gamma antikoerper, tfap2c antikoerper, TFAP2C antikoerper, Smp_157840 antikoerper, Tfap2c antikoerper, tfap2c.S antikoerper

Hintergrund: Tcfap2c is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Tcfap2c binds to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Alias Symbols: Stra2, Ap-2.2, Tcfap2c, AA409384, AP2gamma
Protein Size: 449

Molekulargewicht: 49 kDa

Gen-ID: 21420

NCBI Accession: NM_009335, NP_033361

UniProt: Q61312

Pathways: Stem Cell Maintenance