RUNX1T1 Antikörper (Middle Region)
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- Target Alle RUNX1T1 Antikörper anzeigen
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RUNX1T1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LHSEHPSKRP CTISPGQRYS PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RUNX1T1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RUNX1T1
- Top Product
- Discover our top product RUNX1T1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 567 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Andere Bezeichnung
- RUNX1T1 (RUNX1T1 Produkte)
- Synonyme
- MTG8 antikoerper, si:ch211-232j17.1 antikoerper, wu:fi14b07 antikoerper, zgc:154044 antikoerper, AML1T1 antikoerper, CBFA2T1 antikoerper, CDR antikoerper, ETO antikoerper, ZMYND2 antikoerper, Cbfa2t1h antikoerper, Cbfa2t1 antikoerper, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antikoerper, RUNX1 translocation partner 1 L homeolog antikoerper, RUNX1 translocation partner 1 antikoerper, runx1t1 antikoerper, runx1t1.L antikoerper, RUNX1T1 antikoerper, Runx1t1 antikoerper
- Hintergrund
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RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Alias Symbols: CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1
Protein Interaction Partner: EPS8, NECAB2, ABI3, GSE1, MID2, SPRY2, HOMER3, LPXN, ZMYM4, STX11, MEOX2, CCDC36, TRIM42, SPERT, CREB3L1, LZTS2, EFHC2, CPSF7, C19orf57, PRDM14, CBFA2T2, NCOR1, UBQLN4, ATN1, BCL6, ETS1, RUNX1, DNMT1, SPEN, RBPJ, UBE2E2, UBC, TRIM33, HDAC1, NCOR2, SIN3A,
Protein Size: 604 - Molekulargewicht
- 68 kDa
- Gen-ID
- 862
- NCBI Accession
- NM_175636, NP_783554
- UniProt
- Q06455
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