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EIF2A Antikörper (C-Term)

EIF2A Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Ziege, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776588
  • Target Alle EIF2A Antikörper anzeigen
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    Bindungsspezifität
    • 17
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 83
    • 42
    • 41
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Ziege, Zebrafisch (Danio rerio)
    Wirt
    • 69
    • 15
    Kaninchen
    Klonalität
    • 66
    • 18
    Polyklonal
    Konjugat
    • 45
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF2A Antikörper ist unkonjugiert
    Applikation
    • 66
    • 35
    • 34
    • 33
    • 14
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    DKSPDLAPTP APQSTPRNTV SQSISGDPEI DKKIKNLKKK LKAIEQLKEQ
    Homologie
    Cow: 86%, Dog: 100%, Goat: 83%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EIF2A. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2A
    Top Product
    Discover our top product EIF2A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 585 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Feng, Chen, Chan, Chen: "Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo." in: Parkinson's disease, Vol. 2020, pp. 8814236, (2020) (PubMed).

    Xu, Liu, Caffaro, Hirschberg: "Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24600-8, (2010) (PubMed).

    Su, Wang, Baltzis, Qu, Wong, Koromilas: "Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 1, pp. 63-8, (2006) (PubMed).

  • Target
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    Andere Bezeichnung
    EIF2A (EIF2A Produkte)
    Synonyme
    ATEIF2-A2 antikoerper, EIF2-A2 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, EIF-2A antikoerper, MST089 antikoerper, MSTP004 antikoerper, MSTP089 antikoerper, D030048D22 antikoerper, D3Ertd194e antikoerper, im:7145971 antikoerper, zgc:110460 antikoerper, DDBDRAFT_0185936 antikoerper, DDBDRAFT_0234177 antikoerper, DDB_0185936 antikoerper, DDB_0234177 antikoerper, Eif2a antikoerper, eif2a antikoerper, eif2alpha antikoerper, EIF2A antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eIF2alpha antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, eukaryotic translation initiation factor 2A antikoerper, eukaryotic translation initiation factor 2A, 65kDa antikoerper, eukaryotic translation initiation factor 2A S homeolog antikoerper, eukaryotic translation initiation factor antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2 ALPHA antikoerper, EIF2A antikoerper, Eif2a antikoerper, eif2a antikoerper, eIF2a antikoerper, eif2a.S antikoerper, eif2A antikoerper, eIF-2alpha antikoerper
    Hintergrund
    EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM].
    Alias Symbols: CDA02, MST089, MSTP004, MSTP089, EIF-2A
    Protein Interaction Partner: UBC, CDC20, RPS23, RPS19, RPS16, RPS10, RPS7, RPS5, HDLBP, PRUNE2, EIF3K, SERBP1, RPS29, RPS24, EIF2AK2, MLH1, NXF1, ILF3, PA2G4, APP, PPP1CC, NEDD8, DCC, ATF4,
    Protein Size: 585
    Molekulargewicht
    64 kDa
    Gen-ID
    83939
    NCBI Accession
    NM_032025, NP_114414
    UniProt
    Q9BY44
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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