RNF43 Antikörper (Middle Region)

Produktnummer ABIN2774743

Produktdetails anti-RNF43 Antikörper

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DFDPLVYCSP KGDPQRVDMQ PSVTSRPRSL DSVVPTGETQ VSSHVHYHRH

Homologie: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF43. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF43

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 783 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RNF43 Antikörper (ABIN2774743)

Sugiura, Yamaguchi, Miyamoto: "A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95." in: Experimental cell research, Vol. 314, Issue 7, pp. 1519-28, (2008) (PubMed).

Details zu RNF43

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Andere Bezeichnung: RNF43 (RNF43 Produkte)

Synonyme: RNF124 antikoerper, URCC antikoerper, 4732452J19Rik antikoerper, RGD1305204 antikoerper, ring finger protein 43 antikoerper, RNF43 antikoerper, Rnf43 antikoerper

Hintergrund: RNF43 is a HAP95 (AKAP8L) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer.
Alias Symbols: DKFZp781H02126, DKFZp781H0392, FLJ20315, MGC125630, RNF124, URCC
Protein Interaction Partner: RSPO1, SFPQ, NONO, HECW1, TP53, UBE2D4, KDM5B, UBE2E3, UBE2N, UBE2E1, UBE2D3, UBE2D2, UBE2D1, AKAP8L, UBC,
Protein Size: 783

Molekulargewicht: 86 kDa

Gen-ID: 54894

NCBI Accession: NM_017763, NP_060233

UniProt: Q68DV7

Pathways: WNT Signalweg